Nicolelis教授 脑机接口20年论文集汇总

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Rose小哥今天分享一下Nicolelis教授近20年在神经科学领域的研究成果论文汇总。

Nicolelis教授全名：Miguel NicolelisM.D., Ph.D.，脑机接口的先驱，是杜克大学医学院神经科学特聘教授，他是神经生物、生物医学工程、心理学与神经科学教授，在神经科学领域建树很多。

卷一

基础部分（The Foundation）

基本方法（Essential Methods）

啮齿动物和灵长类动物的实验性脑机接口研究

（Experimental Brain-Machine Interfaces in Rodents and Primates）

卷二

帕金森病和脊髓损伤患者的临床脑机接口研究

（Clinical Brain-Machine Interface Studies in Parkinsonian and Spinal Cord Injury Patients）

帕金森病和癫痫的神经治疗

（Neuroprostheses for Parkinson’s Disease and Epilepsy）

红外老鼠研究论文

（Creating a New Sense: The Infrared Rat Studies Papers）

脑-脑接口和脑（Brain-to-Brain Interfaces and Brainets）

主要意见和评论文章（Key Opinion and Review Articles）

BMI领域综述（A Comprehensive Review of the BMI Field）

卷一

基础部分 The Foundation

[1]Nicolelis MAL, Lin RCS, Woodward DJ, Chapin JK. Induction of immediate spatiotemporal changes in thalamic networks by peripheral block of ascending cutaneous information. Nature 361: 533-536, 1993

[2]Nicolelis MAL, Baccala LA, Lin RCS, Chapin JK. Sensorimotor encoding by synchronous neural ensemble activity at multiple levels of the somatosensory system. Science 268: 1353-1358, 1995

[3]Nicolelis MAL, Ghazanfar AA, Faggin B, Votaw S, Oliveira LMO. Reconstructing the engram: simultaneous, multisite, many single neuron recordings.Neuron 18: 529-537, 1997

[4]Nicolelis MAL, Ghazanfar AA, Stambaugh CH, Oliveira LMO, Laubach M, Chapin JK, Nelson R, Kaas JH. Simultaneous encoding of tactile information by three primate cortical areas. Nature Neurosci 1: 621-630, 1998

[5]Ghazanfar AA, Stambaugh CR, Nicolelis MAL. Encoding of tactile stimulus location by somatosensory thalamocortical ensembles. J Neurosci 20: 3761-3775, 2000

[6]Laubach M, Wessberg J, Nicolelis MAL. Cortical ensemble activity increasingly predicts behavior outcomes during learning of a motor task. Nature 405: 567-571, 2000

[7]Santucci DM, Kralik JD, Lebedev MA, Nicolelis MAL. Frontal and parietal cortical ensembles predict muscle activity during reaching movements in primates.European J Neurosci 22: 1529-1540, 2005

[8]Ramakrishnan A, Byun YW, Rand K, Pedersen C, Lebedev MA, Nicolelis MA. Cortical Neurons Multiplex Reward-Related Signals along with Sensory and Motor Information. Proc Natl Acad Sci. DOI: 10.1073/pnas.1703668114, 2017

基本方法

Essential Methods

[1]Chapin JK, Nicolelis MAL. Principal component analysis of neuronal ensemble activity reveals multidimensional somatosensory representations. J Neurosci Meth 94:121-140, 1999

[2]Laubach M, Shuler M, Nicolelis MAL. Independent component analyses for quantifying neuronal ensemble interactions. J Neurosci Meth 94: 141-154, 1999

[3]Nicolelis MAL, Dimitrov DF, Carmena J, Crist R, Lehew G, Kralik J, Wise S. Chronic, multisite, multielectrode recordings in macaque monkeys. Proc. Natl. Acad. Sci. 100: 11041-11046, 2003

[4]Obeid I., Nicolelis MAL, Wolf P. A low power multichannel analog front end for portable neural signal recordings. J Neurosci Meth 133: 27-32, 2003

[5]Obeid I., Nicolelis MAL, Wolf P. A multichannel telemetry system for single unit neural recordings. J Neurosci Meth 133: 33-38, 2003

[6]Wessberg J, Nicolelis MAL. Optimizing a linear algorithm for real-time robotic control using chronic cortical ensemble recordings in monkeys. J Cogn Neurosci 16:1022-1035, 2004

[7]Li Z, O’Doherty JE, Hanson TL, Lebedev MA, Henriquez CS, Nicolelis MAL. Unscented Kalman Filter for Brain-Machine Interfaces. PLoS One 4: e6243, 2009

[8]Dzirasa K, Fuentes R, Potes JM, Nicolelis MAL. Chronic in vivo multi-circuit neurophysiological recordings in mice. J. Neurosc. Methods 195: 36-46, 2011

[9]Li, Z, O’Doherty, JE, Lebedev, MA, Nicolelis, MAL. Adaptive decoding for brain-machine interfaces through Bayesian parameter updates. Neural Comput. 23: 1–43, 2011

[10]Hanson T, Omarsson B, O’Doherty J, Peikon I, Lebedev M, Nicolelis M. Highside digitally current controlled biphasic bipolar microstimulator. IEEE Trans Neural Syst Rehabil Eng. 20: 331-340, 2012

[11]Schwarz D, Lebedev MA, Tate A, Hanson T, Lehew G, Meloy J, Dimitrov D, Nicolelis MAL. Chronic, Wireless Recordings of Large Scale Brain Activity in Freely Moving Rhesus Monkeys. Nat. Methods. 11: 670-676. doi:10.1038/nmeth.2936,2014

[12]Zacksenhouse M, Lebedev MA, Nicolelis MAL. Signal-Independent Timescale Analysis (SITA) and its Application for Neural Coding during Reaching and Walking. Front. Comput. Neurosci. doi: 10.3389/fncom.2014.00091, 2014

啮齿动物和灵长类动物的实验性脑机接口研究

Experimental Brain-Machine Interfaces in Rodents and Primates

[1]Chapin JK, Moxon KA, Markowitz RS, Nicolelis MAL. Real-time control of a robot arm using simultaneously recorded neurons in the motor cortex. Nature Neurosci 2: 664-670, 1999

[2]Wessberg J, Stambaugh CR, Kralik JD, Beck PD, Chapin JK, Kim J, Biggs SJ, Srinivasan MA, Nicolelis MAL. Real-time prediction of hand trajectory by ensembles of cortical neurons in primates. Nature 408: 361-365, 2000

[3]Carmena JM, Lebedev MA, Crist RE, O’Doherty JE, Santucci DM, Dimitrov DR, Patil PG, Henriquez CS, Nicolelis MAL. Learning to control a brain-machine interface for reaching and grasping by primates. Public Library of Science 1: 193-208,2003

[4]Lebedev MA, Carmena JM, O’Doherty JE, Zacksenhouse M, Henriquez CS,Principe J, Nicolelis MAL. Cortical ensemble adaptation to represent velocity of an artificial actuator controlled by a brain machine interface. J Neurosci 25: 4681-4693,2005

[5]Carmena JM, Lebedev MA, Henriquez CS, Nicolelis MAL. Stable ensemble performance with single neuron variability during reaching movements in primates. J Neurosci 25: 10712-10716, 2005

[6]Fitzsimmons N, Drake W, Hanson T, Lebedev M, Nicolelis MAL. Primate reaching cued by multichannel spatiotemporal cortical microstimulation. J Neurosci 27: 5593-5602, 2007

[7]Zacksenhouse M, Lebedev MA, Carmena JM, O’Doherty JE, Henriquez C, Nicolelis MAL. Cortical modulations increase in early sessions with brain-machine interface. PLoS ONE 2:e619, 2007

[8]Fitzsimmons N, Lebedev MA, Peikon I, Nicolelis MAL. Extracting kinematic parameters for monkey bipedal walking from cortical neuronal ensemble activity. Front. Integr. Neurosci. 3: 1-19, 2009

[9]O’Doherty JE, Lebedev MA, Hanson TL, Fitzsimmons NA, Nicolelis MAL. A brain-machine interface instructed by direct intracortical microstimulation. Front. Integr. Neurosci. 3: 1-10, 2009

[10]O’Doherty JE, Lebedev MA, Ifft PJ, Zhuang KZ, Shokur S, Bleuler H, Nicolelis MAL. Active tactile exploration using a brain-machine-brain interface. Nature 479: 228-231, 2011 [11]Ifft PJ, Lebedev MA, Nicolelis MAL. Cortical Correlates of Fitts’ Law. Front. Integr. Neurosci. 5: 85, 2011

[12]Ifft PJ, Labedev MA, Nicolelis MAL. Reprogramming movements: Extraction of motor intentions from cortical ensemble activity when movement goals change. Front. Neuroeng. 5:16, 2012

[13]Shokur S, O’Doherty J.E., Winans J.A., Bleuler H., Lebedev M.A., Nicolelis M.A.L. Expanding the primate body schema in sensorimotor cortex by virtual touches of an avatar. Proc. Natl. Acad. Sci. 110: 15121-6, doi: 10.1073/pnas.1308459110, 2013

[14]Ifft P, Shokur S, Li Z, Lebedev MA, Nicolelis MAL. A Brain-Machine Interface Enables Bimanual Arm Movements in Monkeys. Sci. Transl. Med. 5: 210, DOI:10.1126/scitranslmed.3006159, 2013

[15]Rajangam S, Tseng P-H, Yin A, Lehew G, Schwarz D, Lebedev MA, Nicolelis MA. Wireless Cortical Brain-Machine Interface for Whole-Body Navigation in Primates. Sci. Rep. doi:10.1038/srep22170, 2016

[16]Yin A, Tseng PH, Rajangam S, Lebedev MA, Nicolelis MAL. Place cell-like activity in the primary sensorimotor and premotor cortex during monkey whole-body navigation. Sci. Rep. doi: 10.1038/s41598-018-27472-4, 2018

卷二

帕金森病和脊髓损伤患者的临床脑机接口研究

Clinical Brain-Machine Interface Studies in Parkinsonian and Spinal Cord Injury Patients

[1]Patil PG, Carmena JM, Nicolelis MAL, Turner DA. Ensemble recordings of human subcortical neurons as a source of motor control signals for a brain-machine interface. J Neurosurgery 55: 27-35, 2004

[2]Hanson TL, Fuller AM, Lebedev MA, Turner DA, Nicolelis MAL. Subcortical Neuronal Ensembles: An Analysis of Motor Task Association, Tremor, Oscillations, and Synchrony in Human Patients. J. Neurosci. 32:8620–8632, 2012

[3]Donati ARC, Shokur S, Morya E, Campos DSF, Moioli RC, Gitti CM, Augusto PB, Tripodi S, Pires CG, Pereira GA, Brasil FL, Gallo S, Lin A, Takigami AK, Aratanha MA, Joshi S, Bleuler H, Cheng G, Rudolph A, Nicolelis MAL. Long-term training with brain-machine interfaces induces partial neurological recovery in paraplegic patients. Sci. Rep. doi: 10.1038/srep30383, 2016

[4]Shokur S, Gallo S, Moioli RC, Donati ARC, Morya E, Bleuler H, Nicolelis MA. Assimilation of virtual legs and perception of floor texture by complete paraplegic patients receiving artificial tactile feedback. Sci. Rep. doi:10.1038/srep32293, 2016

[5]Shokur S, Donati ARC, Campos DSF, Gitti C, Bao G, Fischer D, Almeida S, Braga VAS, Augusto P, Petty C, Alho EJL, Lebediev M, Song AW, Nicolelis MAL. Training with brain-machine interfaces, visuotactile feedback and assisted locomotion improves sensorimotor, visceral, and psychological signs in chronic paraplegic patients. PLoS ONE 13(11): e0206464. https://doi.org/10.1371/journal.pone.0206464,2018

[6]Selfslagh A, Shokur S, Campos D S, Donati A R, Almeida S, Bouri M, Nicolelis M A. Non-invasive, brain-controlled functional electrical stimulation for locomotion rehabilitation in indivduals with paraplegia. Sci. Rep. 9, Article number: 6782, https://doi.org/10.1038/s41598-019-43041-9, 2019

帕金森病和癫痫的神经治疗

Neuroprostheses for Parkinson’s Disease and Epilepsy

[1]Fanselow EE, Reid AP, Nicolelis MAL. Reduction of pentylenetetrazole induced seizure activity in awake rats by seizure-triggered trigeminal nerve stimulation. J Neurosci 20: 8160-8168, 2000

[2]Fuentes R, Petersson P, Siesser WB, Caron MG, Nicolelis MAL. Spinal Cord Stimulation Restores Locomotion in Animal Models of Parkinson’s disease. Science 323: 1578-82, 2009

[3]Yadav AP, Fuentes R, Zhang H, Vinholo T, Wang C-H, Nicolelis MAL. Chronic Spinal Cord Stimulation Protects against 6-hydroxydopamine Lesions. Sci. Rep. 4: 3839. doi: 10.1038/srep03839, 2014

[4]Santana MB, Halje P, Simplicio H, Richter U, Freire M, Petersson P, Fuentes R, Nicolelis MAL. Spinal Cord Stimulation Alleviates Motor Symptoms in a Primate Model of Parkinson’s disease. Neuron 84: 716–722, 2014

[5]Pais-Vieira M, Yadav AP, Moreira D, Guggenmos D, Santos A, Lebedev MA, Nicolelis MA. A Closed Loop Brain-machine Interface for Epilepsy Control Using Dorsal Column Electrical Stimulation. Sci. Rep. doi:10.1038/srep32814, 2016

红外老鼠研究论文

Creating a New Sense: The Infrared Rat Studies Papers

[1]O’Doherty JE, Lebedev MA, Li Z, Nicolelis MAL. Virtual Active Touch Using Randomly Patterned Intracortical Microstimulation. IEEE Trans Neur Syst Rehab Eng. 20: 85-93, 2012

[2]Medina LE, Lebedev MA, O’Doherty JE, Nicolelis MAL. Stochastic Facilitation of Artificial Tactile Sensation in Primates. J. Neurosci. 32: 14271-14275, 2012

[3]Thomson EE, Carra R, Nicolelis MAL. Perceiving Invisible Light through a Somatosensory Cortical Prosthesis. Nat. Commun. 10.1038/ncomms2497, 2013

[4]Hartmann K, Thomson EE, Yun R, Mullen P, Canarick J, Huh A, Nicolelis MA. Embedding a novel representation of infrared light in the adult rat somatosensory cortex through a sensory neuroprosthesis. J. Neurosci. 36:2406 –2424, 2016

[5]Thomson E, Zea I, Windham W, Thenaisie Y, Walker C, Pedowitz P, França W, Graneiro AL, Nicolelis MAL. Cortical Neuroprosthesis Merges Visible and Invisible Light Without Impairing Native Sensory Function. eNeuro DOI: 10.1523/ENEURO.0262-17, 2017

脑-脑接口和脑

Brain-to-Brain Interfaces and Brainets

[1]Pais-Vieira M, Lebedev MA, Kunicki C, Wang J, Nicolelis MAL. A brain-to-brain interface for real-time sharing of sensorimotor information. Sci. Rep. 3:1319, doi:10.1038/srep01319, 2013

[2]Ramakrishnan A, Ifft PJ, Pais-Vieira M, Byun YW, Zhuang KZ, Lebedev MA, Nicolelis MAL. Computing Arm Movements with a Monkey Brainet. Sci. Rep. doi:10.1038/srep10767, 2015

[3]Pais-Vieira M, Chiuffa G, Lebedev MA, Yadav A, Nicolelis MA. Building an organic computing device with multiple interconnected brains. Sci. Rep. doi:10.1038/srep11869, 2015

[4]Tseng P-H, Rajangam S, Lehew G, Lebedev MA, Nicolelis MAL. Interbrain cortical synchronization encodes multiple aspects of social interactions in monkey pairs. Sci. Rep. doi.org/10.1038/s41598-018-22679-x, 2018

主要意见和评论文章

Key Opinion and Review Articles

[1]Nicolelis MAL, Fanselow E, Ghazanfar AA. Hebb’s dream: the resurgence of cell assemblies. Neuron 19: 219-221, 1997

[2]Nicolelis MAL. Actions from thoughts. Nature 409: 403-407, 2001

[3]Nicolelis MAL, Chapin JK. Controlling robots with the mind. Scientific American 287: 24-31, October 2002

[4]Nicolelis MAL. Brain-machine interfaces to restore motor function and probe neural circuits. Nat Rev Neurosci 4: 417-422, 2003

[5]Lebedev MA, Nicolelis MAL. Brain machine interfaces: Past, present and future. Trends Neurosci 29: 536-546, 2006

[6]Nicolelis MAL, Lebedev MA. Principles of Neural Ensemble Physiology Underlying the Operation of Brain-Machine Interfaces. Nat. Rev. Neurosci. 10: 530-540, 2009

[7]Lebedev MA, Tate AJ, Hanson TL, Li Z, O’Doherty JE, Winans JA, Ifft PJ, Zhuang KZ, Fitzsimmons NA, Schwarz DA, Fuller AM, An JH, Nicolelis MA. Future developments in brain-machine interface research. Clinics (Sao Paulo) 66 Suppl 1:25-32, 2011

[8]Lebedev, MA, Nicolelis MAL. Toward a whole body neuroprosthetic. Prog. Brain Res. 194: 47-60, 2011

[9]Nicolelis MA. Mind in Motion. Sci. Am. 307: 58-63, 2012

[10]Nicolelis, MAL. Are we at risk of becoming biological digital machines? Nat. Hum. Behav. 1: Art. 8, DOI: 10.1038/s41562-016-0008, 2017

[11]Yadav A and Nicolelis MAL. Electrical stimulation of the dorsal columns of the spinal cord in Parkinson’s disease. Mov. Disord. doi: 10.1002/mds.27033, 2017

BMI领域综述

A Comprehensive Review of the BMI Field

[1]Lebedev M and Nicolelis MAL. Brain-machine interfaces: from basics science to neuroprosthetic devices, and neurorehabilitation. Physiol. Rev. 97: 767-837,2017