Nature Reviews:肠道屏障与IBD—2020年重磅研究(年度回顾) | 热心肠日报

The intestinal barrier, an arbitrator turned provocateur in IBD

肠道屏障,仲裁者变身IBD煽动者

10.1038/s41575-020-00399-w

12-14, Review

Abstract & Authors:展开

Abstract:收起
Key studies published in 2020 demonstrate that an impaired intestinal barrier precedes clinical diagnosis of inflammatory bowel disease (IBD) by years. Furthermore, studies identify novel regulators of the intestinal barrier, including intestinal macrophages and diurnal variations of diet–microbiome interactions, which could be future therapeutic strategies for IBD.

First Authors:
Saurabh Mehandru

Correspondence Authors:
Jean-Frederic Colombel

All Authors:
Saurabh Mehandru,Jean-Frederic Colombel

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