NGS各种组学建库原理（图解）

、DNA层面各组学建库原理图解：Seq—DNADNA variantsLow levels of DNAEpigeneticsDNA–protein interactionsProtein–protein interactions2、RNA层面各组学建库原理图解：Seq—RNARNA transcriptionRNA–protein interactionsLow levels of RNARNA modificationsRNA structure3、单细胞层面各组学建库原理图解：Seq—Single-CellLow-level RNA detectionLow-level DNA detectionIntegrated DNA and RNA analysis

正文开始啦

1、DNA层面：Seq—DNA

具体分如下几个方向

• DNA variants
• Low levels of DNA

• Epigenetics

CAB-Seq

• DNA–protein interactions

ChIP-Seq

ATAC-Seq

Hi-C 、3-C

• Protein–protein interactions

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2、RNA层面：Seq—RNA

分以下几类：

• RNA transcription

• RNA–protein interactions

• Low levels of RNA

UMI Method

• RNA modifications

• RNA structure

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3、单细胞层面：Seq—Single-Cell

可分以下几个方面：

• Low-level RNA detection

• Low-level DNA detection

• Integrated DNA and RNA analysis

https://www.illumina.com/