每日机理学习-90

问题B019

基本文献

• Yang, B. V.; O'Rourke, D.; Li, J. Synlett. 1993, 195

反应机理

A: Acylationof a tertiary amine. 

B: Attack of chloride ion on thebenzylic position.

C: E1 elimination ofthe chloride followed by addition ofmethanol,

D: Elimination of the carbamic acid helped by the oxygen lone pairof the methoxy group.

E: Decarboxylation.

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