读书笔记丨长三角肺癌之光-中国肺癌原创临床研究阶段汇总

读书笔记丨感恩并传承CTONG-中国肺癌原创临床研究

写意人物丨陆舜教授:从PI的角度看中国创新药的发展

陆舜教授:有的放矢,做肺癌研究领域的“领潮儿”

陆舜教授:沃利替尼有望成为首个代表中国走向全球的肺癌靶向创新药物

江浙沪地区历届重要肺癌论坛汇总(长三角地区肺癌论坛系列)

长三角肺癌协作组青年博士团队组织框架介绍

齐聚浙江嘉兴,长三角肺癌再续新篇章——浙江省基层肺癌协作组成立

历史回顾丨浙江省肿瘤医院胸部肿瘤青年医师精彩亮相2016WCLC

走进中国科学院大学附属肿瘤医院(浙江省肿瘤医院)I期临床试验病房

中国科学院大学附属肿瘤医院(浙江省肿瘤医院)I期临床试验病房进修人员招聘公告

长三角实体瘤病友交流群系列全面上线

Lancet Respir Med

Lancet Respir Med Once-daily savolitinib in Chinese patients with pulmonary sarcomatoid carcinomas and other non-small-cell lung cancers harbouring MET exon 14 skipping alterations: a multicentre, single-arm, open-label, phase 2 study  Shun Lu(2021)

Transl Lung Cancer Res

Transl Lung Cancer Res Fruquintinib with gefitinib as first-line therapy in patients carrying EGFR mutations with advanced non-small cell lung cancer: a single-arm, phase II study  Shun Lu(2021)

Ann Transl Med (TEINE, CTONG-0904)

Ann Transl Med Docetaxel maintenance therapy versus best supportive care after first-line chemotherapy with different dose docetaxel plus cisplatin for advanced non-small cell lung cancer (TFINE study, CTONG-0904): an open-label, randomized, phase III trial Shun Lu(2021)

J Thorac Oncol(RATIONALE 304)

J Thorac Oncol Tislelizumab plus chemotherapy as first-line treatment for locally advanced or metastatic nonsquamous non-small cell lung cancer (RATIONALE 304):A randomized phase 3 trial Shun Lu(2021)

J Thorac Oncol

J Thorac Oncol Efficacy and safety of Niraparib as maintenance treatment in patients with extensive-stage small cell lung cancer after first-line chemotherapy:a randomized, double-blind,phase 3 study Shun Lu(2021)

JAMA Oncol(RATIONALE 307)

JAMA Oncol Tislelizumab plus chemotherapy vs chemotherapy alone as first-line treatment for advanced squamous non-small-cell lung cancer A phase 3 randomized clinical trial  Shun Lu(2021)

Lung Cancer

Lung Cancer Nivolumab versus docetaxel in a predominantly Chinese patient population with previously treated advanced non-small cell lung cancer: 2-year follow-up from a randomized, open-label, phase 3 study (CheckMate 078) Shun Lu (2020)

Clin Cancer Res

Clin Cancer Res Clonal architecture of EGFR mutation predicts the efficacy of EGFR-Tyrosine Kinase Inhitors in advanced NSCLC: a prospective multicenter study (NCT03059641) Shun Lu (2020)

Lung Cancer (FALUCA)

Lung Cancer A phase III, randomized, double-blind, placebo-controlled, multicenter study of fruquintinib in Chinese patients with advanced nonsquamous non-small-cell lung cancer-the FALUCA study Shun Lu (2020)

J Clin Oncol

J Clin Oncol  Randomized, double-blind, placebo-controlled, multicenter phase II study of fruquintinib after two prior chemotherapy regimens in Chinese patients with advanced nonsquamous non-small-cell lung cancer  Shun Lu (2018)

J Thorac Oncol

J Thorac Oncol  Nedaplatin plus docetaxel versus cisplatin plus docetaxel as first-line chemotherapy for advanced squamous cell carcinoma of the lung-A multicenter, open-label, randomized, phase III trial Shun Lu (2018)

Ann Oncol(East Asia S-1)

Ann Oncol Randomized controlled trial of S-1 versus docetaxel in patients with non-small-cell lung cancer previously treated with platinum-based chemotherapy (East Asia S-1 Trial in Lung Cancer)  Shun Lu (2017)

J Thorac Oncol

J Thorac Oncol A multicenter, open-label, randomized phase II controlled study of rh-Endostatin (Endostar) in combination with chemotherapy in previously untreated extensive-stage small-cell lung cancer Shun Lu (2015)

Chin Med J

Chin Med J Gemcitabine and cisplatin treatment over a 3-week versus a 4-week dosing schedule: a randomized trial conducted in Chinese patients with nonsmall cell lung cancer  Mei-lin Liao (2008)

临床试验-转化研究闭环式研究平台建设

1.基因多平台检测平台搭建(转化研究)

2.样本库平台搭建(转化研究)

3.罕见靶点类器官模型临床前研究平台搭建(临床试验+转化研究)

4.罕见靶点富集互联网医院平台搭建临床试验+转化研究)

心路历程

心路历程1:  2019.12   长三角肺癌协作组成立

心路历程2:  2020.04   长三角肺癌协作组临床试验招募启动

心路历程3:  2020.07   长三角肺癌协作组青年医师巡讲团成立

心路历程4:  2021.01   长三角肺癌协作组青年博士团队成立

心路历程5:  2021.03   江苏省基层肺癌协作组成立

心路历程6:  2021.04   长三角肺癌基因多平台检测实验室揭牌

心路历程7:  2021.05   浙江省基层肺癌协作组成立

心路历程8:2021.07   长三角肺癌多中心研究样本库建立

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