克利夫兰特邀述评：关于肠道微生物，我们已知与未知

　　在过去十年中，关于人体肠道微生物的研究已经展开。虽然胃肠道曾经仅仅被作为一种消化器官，但是新技术导致科学界考虑有关肠道微生物可能对人类健康和疾病的影响。现在，肠道微生物在代谢、免疫防御和行为中的作用已众所周知。从子宫内到分娩后，我们的肠道微生物随着年龄、环境、应激、饮食、健康状况以及药物暴露而迅速发生变化。本文回顾了对于肠道微生物目前已知的各种影响，以期鼓励读者进一步探索其他未知的。

Nutr Clin Pract. 2015 Dec;30(6):734-46.

Gut Microbiome: What We Do and Don't Know.

Cresci GA, Bawden E.

Cleveland Clinic, Cleveland, Ohio.

Within the last decade, research regarding the human gut microbiome has exploded. While the gastrointestinal tract was once regarded simply as a digestive organ, new technologies have led the science world to wonder about the impact that the gut microbiota may have on human health and disease. The gut microbiome is now becoming known for its role in metabolism, immune defense, and behavior. From in utero variations to those that rapidly occur post partum, our gut microbiome changes with age, environment, stress, diet, and health status as well as medication exposure. This article reviews what is currently known regarding various influences on the gut microbiome and is meant to encourage the reader to further explore the unknown.

KEYWORDS: antibiotics; chronic disease; diet; health; immunity; life cycle stages; microbiota

PMID: 26449893

DOI: 10.1177/0884533615609899