Dave W. C. MacMillan 当代化学大师
标签
Synthesis and Methods
Photoredox
OrganoCatalysis
Total Synthesis
简介
荣誉奖励
研究领域
探索催化领域的新概念:有机催化、级联反应、协同反应、光氧化还原和金属氧化还原催化及其在天然产物和药物的全合成中的应用。
代表著作
1)Collective synthesis of natural products by means of organocascade catalysis
2)Total Synthesis and Structural Revision of Callipeltoside C
3)Catalyst-controlled oligomerization for the collective synthesis of polypyrroloindoline natural products
Recent Publications
1)Copper-mediated synthesis of drug-like bicyclopentanes
2)The merger of decatungstate and copper catalysis to enable aliphatic C(sp3 )–H trifluoromethylation
3)Direct arylation of strong aliphatic C–H bonds
4)Decarboxylative sp3 C–N coupling via dual copper and photoredox catalysis
5)Two-Step Synthesis of Carbohydrates by Selective Aldol Reactions
6)Discovery of an a-Amino C–H Arylation Reaction Using the Strategy of Accelerated Serendipity
7)A radical approach to the copper oxidative addition problem: Trifluoromethylation of bromoarenes
8)Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis
9)Metallaphotoredox-Catalyzed Cross-Electrophile Csp 3 −Csp 3 Coupling of Aliphatic Bromides
10)Spin-Center Shift-Enabled Direct Enantioselective α‑Benzylation of Aldehydes with Alcohols
人才培养
Dave W. C. Macmillan作为目前化学学术界的活跃大牛,同时也培养了很多杰出的子弟,一下列举部分:
评论
Dave W. C. Macmillan是一位非常高产的化学家,从其在顶级期刊《Science》《Nature》接连不断地发表自己地研究成果可见一斑。研究工作做得非常漂亮,并且研究成果的成果转化也是非常值得学习。
阅读其研究成果,真的有一种追剧的感觉,正所谓:Macmillan出品,必为精品!
参考
http://chemlabs.princeton.edu/macmillan/