科研实验中的抗体偶联药物结合物:DBCO-PEG4-vc-PAB系列及Gly3-MMAF、Gly5-Ahx-DM1
抗体(antibody)毒素(drug)连接物(linker)构建ADC-抗体药物偶连物
ADCs的组成包括肿瘤抗原特异性mAb，稳定的可裂解或不可裂解的linker，以及有效的细胞毒性载荷。 rug)、连接物(linker)构建ADC-抗体药物偶连物
ADCs的组成包括肿瘤抗原特异性mAb，稳定的可裂解或不可裂解的linker，以及有效的细胞毒性载荷。
ADC由以下三部分组成：
抗体（antibody）：其作用是特异性识别靶细胞
毒素（drug）：起到损伤细胞的作用
连接物（linker）：连接抗体与毒素
相关资料：
DBCO-PEG4-vc-PAB-MMAE
DBCO-PEG4-MMAF
DBCO-PEG4-Ahx-DM1
DBCO-PEG4-vc-PAB-Duocarmycin SA
DBCO-PEG4-vc-PAB-(PEG2)-Duocarmycin SA
DBCO-PEG4-VA-PBD
DBCO-PEG4-vc-PAB-MMAF
DBCO-PEG4-vc-PAB-MMAD
DBCO-PEG4-vc-PAB-Duocarmycin TM
DBCO-PEG4-vc-PAB-(PEG2)-Duocarmycin TM
DBCO-PEG4-vc-PAB-Duocarmycin DM
DBCO-PEG4-vc-PAB-(PEG2)-Duocarmycin DM
DBCO-PEG4-VC-PAB-DMAE-PNU159682
DBCO-PEG4-DMAE-PNU159682
DBCO-PEG4-GGFG-DX8951
DBCO-PEG4-vc-PAB-Ahx-DM1
DBCO-PEG8-VA-PAB-SG3199
Gly3-vc-PAB-MMAE
Gly3-MMAF
Gly5-Ahx-DM1
PNU159682-EDA-Gly3
ADC pre-screening kit A
Protein A-DM1
Protein A-MMAE
Protein A-MMAF
Protein A-Duocarmycin
Protein A-Calicheamicin
Protein A-PBD
ADC pre-screening kit G
Protein G-DM1
Protein G-MMAE
Protein G-MMAF
Protein G-Duocarmycin
Protein G-Amanitin
Protein G-Amanitin
Rabbit Anti-vc-PAB-MMAE pAb
Mouse Anti-vc-PAB-MMAE mAb (B11F11)
Rabbit Anti-MMAF pAb
Mouse Anti-MMAF mAb (F3B11)
Mouse Anti-MMAE / F mAb (B12A2)
Mouse Anti-MMAE /F mAb (C12A1)
Rabbit Anti-DM1/4 pAb
Mouse Anti-DM1/4 mAb (F1D5)
Mouse Anti-DM1/4 mAb (G2F3)
Rabbit Anti-Calicheamicin pAb
Mouse Anti-Calicheamicin mAb (B1G9)
Mouse Anti-Calicheamicin mAb (C1F12)
Rabbit Anti-Duocarmycin pAb
Mouse Anti-Duocarmycin mAb (E11A1)
Mouse Anti-Duocarmycin mAb (H7A9)
Mouse Anti-Duocarmycin mAb (E6B3)
Rabbit Anti-PNU-159682 pAb
Mouse Anti-PNU-159682 mAb (F7F2)
Mouse Anti-PNU-159682 mAb (C1E3)
Mouse Anti-PNU-159682 mAb (D12H11)
Rabbit Anti-Amanitin pAb
Mouse Anti-Amanitin mAb (H3E1)
Mouse Anti-Amanitin mAb (H12D6)
Mouse Anti-Amanitin mAb (C2C4)
Rabbit Anti-SN38 pAb
Mouse Anti-SN38 mAb (10F11A9D6)
Mouse Anti-SN38 mAb (8E10F12F3)
Mouse Anti-SN38 mAb (8E10A4A1)
Rabbit Anti-PBD SG3199 pAb
Mouse Anti-PBD SG3199 (7H6H9A6) mAb
Mouse Anti-PBD SG3199 (8G2H12A9) mAb
Mouse Anti-PBD SG3199 (8B3D12G1) mAb
资料仅供科研参考，其他合成技术疑问欢迎探讨(2021.4.lrx )