欧洲肠外肠内营养学会（ESPEN）痴呆营养指南（正式版）
Clin Nutr. 2015 Dec;34(6):1052-1073.
ESPEN guidelines on nutrition in dementia.
Volkert D, Chourdakis M, Faxen-Irving G, Frühwald T, Landi F, Suominen MH, Vandewoude M, Wirth R, Schneider SM.
Friedrich-Alexander-Universitat (FAU) Erlangen-Nürnberg, Nuremberg, Germany.
Aristotle University of Thessaloniki (AUTH), Greece.
Karolinska Institutet, Stockholm, Sweden.
Krankenhaus Hietzing, Vienna, Austria.
Catholic University of the Sacred Heart, Rome, Italy.
Helsinki University Central Hospital, Helsinki, Finland.
Medical School, University of Antwerp, Belgium.
St. Marien-Hospital Borken, Borken, Germany.
Centre Hospitalier Universitaire de Nice, Nice, France.
BACKGROUND: Older people suffering from dementia are at increased risk of malnutrition due to various nutritional problems, and the question arises which interventions are effective in maintaining adequate nutritional intake and nutritional status in the course of the disease. It is of further interest whether supplementation of energy and/or specific nutrients is able to prevent further cognitive decline or even correct cognitive impairment, and in which situations artificial nutritional support is justified.
OBJECTIVE: It is the purpose of these guidelines to cover these issues with evidence-based recommendations.
METHODS: The guidelines were developed by an international multidisciplinary working group in accordance with officially accepted standards. The GRADE system was used for assigning strength of evidence. Recommendations were discussed, submitted to Delphi rounds and accepted in an online survey among ESPEN members.
RESULTS: 26 recommendations for nutritional care of older persons with dementia are given. In every person with dementia, screening for malnutrition and close monitoring of body weight are recommended. In all stages of the disease, oral nutrition may be supported by provision of adequate, attractive food in a pleasant environment, by adequate support and elimination of potential causes of malnutrition. Supplementation of single nutrients is not recommended unless there is a sign of deficiency. Oral nutritional supplements are recommended to improve nutritional status but not to correct cognitive impairment or prevent cognitive decline. Artificial nutrition is suggested in patients with mild or moderate dementia for a limited period of time to overcome a crisis situation with markedly insufficient oral intake, if low nutritional intake is predominantly caused by a potentially reversible condition, but not in patients with severe dementia or in the terminal phase of life.
CONCLUSION: Nutritional care and support should be an integral part of dementia management. In all stages of the disease, the decision for or against nutritional interventions should be made on an individual basis after carefully balancing expected benefit and potential burden, taking the (assumed) patient will and general prognosis into account.
PII: S0261-5614(15)00237-X
DOI: 10.1016/j.clnu.2015.09.004