高纤维橙汁作为女性营养补充：耐受性和效果的随机、双盲、安慰剂对照研究

　　背景：人们膳食纤维的每日摄取量通常低于推荐量。通过一项双盲、对照、随机研究，我们对富含纤维的橙汁作为女性纤维补充剂的效果和耐受性进行了评估。

　　资料与方法：在非干预性观察1周后，192例健康成年女性每天摄取400ml不含（安慰剂组）或富含纤维（纤维组）的橙汁，坚持使用21天。在研究期间，记录其每天的橙汁摄入量并控制每周摄入量。常量营养素，纤维素，以及能量的摄入量根据3天食物记录、经过验证的食物化学组成数据库、以及“ProDiet”软件来确定。胃肠症状通过个人进行症状强度的4等级评分，并通过直观的类比标度来对疼痛严重程度分级。

　　结果：常量营养素和能量的摄入并没有发生变化。对照组（n=97）总纤维摄入的记录低于每日推荐值。与之相比，纤维组（n=95）总的摄取值较高，同时可溶性纤维的摄取量达到了每日纤维摄取的推荐量。两组均有报道：随着时间的延长，轻度腹胀和隆隆声的出现频率有所增加（P≤0.05）。同时，随着时间的延长，纤维组发生轻度腹胀的频率更高（P=0.002）。

　　结论：摄取富含纤维的橙汁对女性达到每日推荐纤维剂量是有效的，不伴有强烈的副作用，可以将其推荐为一种女性补充纤维摄取量的合理方法。

JPEN J Parenter Enteral Nutr. 2015 Nov;39(8):941-7.

High-Fiber Orange Juice as a Nutrition Supplement in Women: A Randomized, Double-Blind, Placebo-Controlled Study of Tolerance and Effectiveness.

Bergamasco C, Horie LM, Torrinhas RS, Waitzberg DL.

Department of Gastroenterology, Surgical Gastroenterology Discipline (LIM 35), University of Sao Paulo School of Medicine, Brazil.

GANEP-Nutricao Humana, Sao Paulo, Brazil.

NAPAN-Grupo de Apoio à Pesquisa em Alimentos e Nutricao, University of Sao Paulo, Sao Paulo, Brazil.

BACKGROUND: The daily consumption of dietary fiber is frequently below suggested recommendations. Using a double-blind, controlled, randomized study, we assessed the efficiency and tolerance of a fiber-enriched orange juice to supplement fiber intake in women.

MATERIALS AND METHODS: After 1 week of noninterventional observation, 192 healthy adult women ingested 400 mL of orange juice for 21 days, which either was not (placebo group) or was enriched with fiber (fiber group). Orange juice ingestion was registered daily and controlled for each week during the study period. Macronutrient, fiber, and energy intake were determined using a 3-day food record, validated food chemical composition databases, and the "Pro Diet" software. Gastrointestinal symptoms were self-evaluated daily by scoring 4 grades of symptom intensity and using a visual analog scale to grade pain severity.

RESULTS: No changes were observed for macronutrient and energy ingestion. For the placebo group (n = 97), the total fiber intake record was under the daily recommended value. In contrast, the fiber group (n = 95) displayed higher comparative values of total and soluble fiber consumption (P ≤ .001), achieving the daily recommended values of fiber intake. Both groups reported an increased frequency of slight bloating and rumbles over time (P ≤ .05). The fiber group also experienced a higher frequency of slight flatulence over time (P = .002).

CONCLUSION: Consumption of fiber-enriched orange juice was efficient to achieve the daily fiber intake recommendation for women, was not accompanied by intense adverse events, and may represent a suitable method to supplement fiber intake in woman.

KEYWORDS: fiber; orange juice; tolerance

PMID: 24941951

DOI: 10.1177/0148607114539703