遇到不靠谱的外包公司太惨了，一图多卖

临床医生做科研，说真的，实在太累了，特别是做基础科研的医生。做基础科研基本上都是要与小白鼠、细胞这些打交道，需要消耗大量的时间和精力，而临床医生往往都是比较忙的，根本没有时间做实验。如果自己职称比较高，有自己的研究生还好，可以把实验交给学生来做；如果没有研究生的话，很多临床医生往往都是会选择交给外包公司来做。

选择外包公司来做实验最怕就是遇到不靠谱的公司，一些不靠谱的外包公司往往都将结果图片卖给多个课题组或者个人，一份结果图片发了N篇SCI。下面这篇文章就是因为一份图片与额外9篇文章的图片有重复而被撤稿。

文章题目：Retraction Note to: Chrysophanol exhibits anti-cancer activities in lung cancer cell through regulating ROS/HIF-1a/VEGF signaling pathway

官方撤稿理由：

Figure 2A appears to contain the same images that have been published elsewhere with different labels: Figure 6K (Yin et al. 2020) and Figure 3E ((Liu 2018), retracted).

Figure 2E images labelled as A549 cells appears to be similar to that published elsewhere with different labels: Figure 4K (Yin et al. 2020) and Figure 2E (Wang et al. 2018).

Figure 3G - overlap in images used in this and another unrelated article by other authors (Wang et al. 2019)

Figure 6A appears to contain images that have been published elsewhere with different labels: Figure 8B in ((Liu 2018), retracted), Figure 6A (Sun et al. 2020), Figure 7A in (Niu et al. 2019), and Figure 6A ((Gao 2017), retracted).

Figure 6E appears to contain images that have been published elsewhere with different labels: Figure 6D (Sun et al. 2020) and Figure 6C (Han et al. 2019).

Figure 6K appears to contain images that have been published elsewhere with different labels (Sun et al. 2020)

The authors were unable to provide raw data and stated that the figures were produced by a commercial lab hired to perform some of the experiments for this study（作者无法提供原始数据，并指出这些图片是由一家商业实验室提供的）. Furthermore, the authors stated that some of the data presented were not generated as part of this study. The Editor-in-Chief therefore no longer has confidence in the integrity of the data in this article.

All authors agree to this retraction.

参考文献：

1、Retracted article: Gao MQ et al. (2017) Hispidulin suppresses tumor growth and metastasis in renal cell carcinoma by modulating ceramide-sphingosine 1-phosphate rheostat. Am J Cancer Res 7(7):1501-1514

2、Han M, Gao H, Xie J et al (2019) Hispidulin induces ER stress-mediated apoptosis in human hepatocellular carcinoma cells in vitro and in vivo by activating AMPK signaling pathway. Acta Pharmacol Sin 40:666–676. https://doi.org/10.1038/s41401-018-0159-7

3、Retracted article: Liu K. et al. (2018) Hispidulin suppresses cell growth and metastasis by targeting PIM 1 through JAK 2/STAT 3 signaling in colorectal cancer. Cancer Sci. https://doi.org/10.1111/cas.13575

4、Niu Y et al (2019) Physcion 8-O-β-glucopyranoside induced ferroptosis via regulating miR-103a-3p/GLS2 axis in gastric cancer. Life Sciences V237:116893. https://doi.org/10.1016/j.lfs.2019.116893

5、Sun Y, Lv B, Zhang X (2020) Knock-down of LncRNA-XIST induced glioma cell death and inhibited tumorigenesis by regulating miR-137/SLC1A5 axis-mediated ROS production. Naunyn-Schmiedeberg’s Arch Pharmacol. https://doi.org/10.1007/s00210-020-01831-3

6、Wang N et al (2018) Euxanthone suppresses tumor growth and metastasis in colorectal cancer via targeting CIP2A/PP2A pathway. Life Sci 209:498–506. https://doi.org/10.1016/j.lfs.2018.08.052

7、Wang L, Wang J, Zhao H et al (2019) Soyasapogenol B exhibits anti-growth and anti-metastatic activities in clear cell renal cell carcinoma. Naunyn-Schmiedeberg’s Arch Pharmacol 392:551–563. https://doi.org/10.1007/s00210-018-01607-w

8、Yin J, Yin Q, Liang B et al (2020) Chrysophanol suppresses growth and metastasis of T cell acute lymphoblastic leukemia via miR-9/PD-L1 axis. Naunyn-Schmiedeberg’s Arch Pharmacol 393:273–286. https://doi.org/10.1007/s00210-019-01778-0

9、Zhang J, Wang Q, Wang Q et al (2020) Chrysophanol exhibits anti-cancer activities in lung cancer cell through regulating ROS/HIF-1a/VEGF signaling pathway. Naunyn-Schmiedeberg’s Arch Pharmacol 393:469–480. https://doi.org/10.1007/s00210-019-01746-8